Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Targeting TLR4 and CXCL2

OBJECTIVE: Systemic lupus erythematosus (SLE) is an autoimmune disease with complex etiology that is not yet entirely understood. We aimed to elucidate the mechanisms and therapeutic potential of microRNAs (miRNAs) in SLE in a Tibetan population. METHODS: Peripheral blood mononuclear cells from SLE...

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Detalles Bibliográficos
Autores principales: Yang, Binbin, Huang, Xinwei, Xu, Shuangyan, Li, Li, Wu, Wei, Dai, Yunjia, Ge, Ming-Xia, Yuan, Limei, Cao, Wenting, Yang, Meng, Wu, Yongzhuo, Deng, Danqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552026/
https://www.ncbi.nlm.nih.gov/pubmed/34721432
http://dx.doi.org/10.3389/fimmu.2021.756825

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