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MALT1-Dependent Cleavage of HOIL1 Modulates Canonical NF-κB Signaling and Inflammatory Responsiveness

Nuclear factor kappa B (NF-κB) is a critical transcription factor involved in regulating cell activation, inflammation, and survival. The linear ubiquitin chain assembly complex (LUBAC) which consists of HOIL1, HOIP, and SHARPIN, catalyzes the linear ubiquitination of target proteins—a post-translat...

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Detalles Bibliográficos
Autores principales:	Fung, Shan-Yu, Lu, Henry Y., Sharma, Mehul, Sharma, Ashish A., Saferali, Aabida, Jia, Alicia, Abraham, Libin, Klein, Theo, Gold, Michael R., Noterangelo, Luigi D., Overall, Christopher M., Turvey, Stuart E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552041/ https://www.ncbi.nlm.nih.gov/pubmed/34721419 http://dx.doi.org/10.3389/fimmu.2021.749794

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