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DREAM represses distinct targets by cooperating with different THAP domain proteins

The DREAM (dimerization partner [DP], retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell-cycle and other genes, but its mechanism of action is unclear. Here, we demonstrate that two C. elegans THAP domain proteins, LIN-15B and LIN-36, co-localize with DR...

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Detalles Bibliográficos
Autores principales: Gal, Csenge, Carelli, Francesco Nicola, Appert, Alex, Cerrato, Chiara, Huang, Ni, Dong, Yan, Murphy, Jane, Frapporti, Andrea, Ahringer, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552245/
https://www.ncbi.nlm.nih.gov/pubmed/34686342
http://dx.doi.org/10.1016/j.celrep.2021.109835