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A pH and Mg(2+)-Responsive Molecular Switch Based on a Stable DNA Minidumbbell Bearing 5′ and 3′-Overhangs

[Image: see text] Minidumbbell (MDB) is a non-B DNA structure of which the thermodynamic stability is sensitive to a chemical environment such as pH, serving as a potential structural motif in constructing DNA-based molecular switches. This work aims to design thermodynamically stable MDB structures...

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Detalles Bibliográficos
Autores principales: Zhang, Jiacheng, Wang, Yang, Wan, Liqi, Liu, Yuan, Yi, Jie, Lam, Sik Lok, Guo, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552455/
https://www.ncbi.nlm.nih.gov/pubmed/34723023
http://dx.doi.org/10.1021/acsomega.1c04346