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Prospective Tracking of Donor-Reactive T-Cell Clones in the Circulation and Rejecting Human Kidney Allografts

BACKGROUND: Antigen recognition of allo-peptides and HLA molecules leads to the activation of donor-reactive T-cells following transplantation, potentially causing T-cell-mediated rejection (TCMR). Sequencing of the T-cell receptor (TCR) repertoire can be used to track the donor-reactive repertoire...

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Detalles Bibliográficos
Autores principales:	Aschauer, Constantin, Jelencsics, Kira, Hu, Karin, Heinzel, Andreas, Gregorich, Mariella Gloria, Vetter, Julia, Schaller, Susanne, Winkler, Stephan M., Weinberger, Johannes, Pimenov, Lisabeth, Gualdoni, Guido A., Eder, Michael, Kainz, Alexander, Troescher, Anna Regina, Regele, Heinz, Reindl-Schwaighofer, Roman, Wekerle, Thomas, Huppa, Johannes Bernhard, Sykes, Megan, Oberbauer, Rainer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552542/ https://www.ncbi.nlm.nih.gov/pubmed/34721420 http://dx.doi.org/10.3389/fimmu.2021.750005

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