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Identification of the Biosynthetic Gene Cluster for the Organoarsenical Antibiotic Arsinothricin

The soil bacterium Burkholderia gladioli GSRB05 produces the natural compound arsinothricin [2-amino-4-(hydroxymethylarsinoyl) butanoate] (AST), which has been demonstrated to be a broad-spectrum antibiotic. To identify the genes responsible for AST biosynthesis, a draft genome sequence of B. gladio...

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Detalles Bibliográficos
Autores principales:	Galván, Adriana E., Paul, Ngozi P., Chen, Jian, Yoshinaga-Sakurai, Kunie, Utturkar, Sagar M., Rosen, Barry P., Yoshinaga, Masafumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552651/ https://www.ncbi.nlm.nih.gov/pubmed/34378964 http://dx.doi.org/10.1128/spectrum.00502-21

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