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The KSHV ORF20 Protein Interacts with the Viral Processivity Factor ORF59 and Promotes Viral Reactivation

Upon Kaposi’s Sarcoma-associated herpesvirus (KSHV) lytic reactivation, rapid and widespread amplification of viral DNA (vDNA) triggers significant nuclear reorganization. As part of this striking shift in nuclear architecture, viral replication compartments are formed as sites of lytic vDNA product...

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Detalles Bibliográficos
Autores principales: Hoffman, D., Rodriguez, W., Macveigh-Fierro, D., Miles, J., Muller, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552657/
https://www.ncbi.nlm.nih.gov/pubmed/34106579
http://dx.doi.org/10.1128/spectrum.00145-21

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