SARS-CoV-2 Quasispecies Provides an Advantage Mutation Pool for the Epidemic Variants

The dynamics of quasispecies afford RNA viruses a great fitness on cell tropism and host range. To study the quasispecies features and the intra-host evolution of SARS-CoV-2, we collected nine confirmed patients and sequenced the haplotypes of spike gene using a single-molecule real-time platform. F...

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Detalles Bibliográficos
Autores principales: Sun, Fengming, Wang, Xiuhua, Tan, Shun, Dan, Yunjie, Lu, Yanqiu, Zhang, Juan, Xu, Junli, Tan, Zhaoxia, Xiang, Xiaomei, Zhou, Yi, He, Weiwei, Wan, Xing, Zhang, Wei, Chen, Yaokai, Tan, Wenting, Deng, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552775/
https://www.ncbi.nlm.nih.gov/pubmed/34346744
http://dx.doi.org/10.1128/spectrum.00261-21

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