Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR

Accurate and timely diagnosis of SARS-CoV-2 is a critical step toward controlling the viral spread, since it facilitates the identification and isolation of infected individuals. Mutations in the primer-/probe-binding sites may lead to false-negative results.

Detalles Bibliográficos
Autores principales: Hasan, Rashedul, Hossain, Mohammad Enayet, Miah, Mojnu, Hasan, Md Mahmudul, Rahman, Mustafizur, Rahman, Mohammed Ziaur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552787/
https://www.ncbi.nlm.nih.gov/pubmed/34431705
http://dx.doi.org/10.1128/spectrum.00545-21
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author Hasan, Rashedul
Hossain, Mohammad Enayet
Miah, Mojnu
Hasan, Md Mahmudul
Rahman, Mustafizur
Rahman, Mohammed Ziaur
author_facet Hasan, Rashedul
Hossain, Mohammad Enayet
Miah, Mojnu
Hasan, Md Mahmudul
Rahman, Mustafizur
Rahman, Mohammed Ziaur
author_sort Hasan, Rashedul
collection PubMed
description Accurate and timely diagnosis of SARS-CoV-2 is a critical step toward controlling the viral spread, since it facilitates the identification and isolation of infected individuals. Mutations in the primer-/probe-binding sites may lead to false-negative results.
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spelling pubmed-85527872021-11-08 Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR Hasan, Rashedul Hossain, Mohammad Enayet Miah, Mojnu Hasan, Md Mahmudul Rahman, Mustafizur Rahman, Mohammed Ziaur Microbiol Spectr Letter to the Editor Accurate and timely diagnosis of SARS-CoV-2 is a critical step toward controlling the viral spread, since it facilitates the identification and isolation of infected individuals. Mutations in the primer-/probe-binding sites may lead to false-negative results. American Society for Microbiology 2021-08-25 /pmc/articles/PMC8552787/ /pubmed/34431705 http://dx.doi.org/10.1128/spectrum.00545-21 Text en Copyright © 2021 Hasan et al. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Letter to the Editor
Hasan, Rashedul
Hossain, Mohammad Enayet
Miah, Mojnu
Hasan, Md Mahmudul
Rahman, Mustafizur
Rahman, Mohammed Ziaur
Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR
title Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR
title_full Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR
title_fullStr Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR
title_full_unstemmed Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR
title_short Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR
title_sort identification of novel mutations in the n gene of sars-cov-2 that adversely affect the detection of the virus by reverse transcription-quantitative pcr
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552787/
https://www.ncbi.nlm.nih.gov/pubmed/34431705
http://dx.doi.org/10.1128/spectrum.00545-21
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