Kir4.1 is coexpressed with stemness markers in activated astrocytes in the injured brain and a Kir4.1 inhibitor BaCl(2) negatively regulates neurosphere formation in culture

Astrocytes are activated in response to brain damage. Here, we found that expression of Kir4.1, a major potassium channel in astrocytes, is increased in activated astrocytes in the injured brain together with upregulation of the neural stem cell markers, Sox2 and Nestin. Expression of Kir4.1 was als...

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Detalles Bibliográficos
Autores principales: Kwon, Jae-Kyung, Choi, Dong-Joo, Yang, Haijie, Ko, Dong Wan, Jou, Ilo, Park, Sang Myun, Joe, Eun-Hye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552822/
https://www.ncbi.nlm.nih.gov/pubmed/34697267
http://dx.doi.org/10.4196/kjpp.2021.25.6.565

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