An experience on the model-based evaluation of pharmacokinetic drug-drug interaction for a long half-life drug

Fixed-dose combinations development requires pharmacokinetic drug-drug interaction (DDI) studies between active ingredients. For some drugs, pharmacokinetic properties such as long half-life or delayed distribution, make it difficult to conduct such clinical trials and to estimate the exact magnitud...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Yunjung, Jeon, Sangil, Choi, Suein, Han, Sungpil, Park, Maria, Han, Seunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552828/
https://www.ncbi.nlm.nih.gov/pubmed/34697265
http://dx.doi.org/10.4196/kjpp.2021.25.6.545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552828/
https://www.ncbi.nlm.nih.gov/pubmed/34697265
http://dx.doi.org/10.4196/kjpp.2021.25.6.545

Ejemplares similares