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An experience on the model-based evaluation of pharmacokinetic drug-drug interaction for a long half-life drug

Fixed-dose combinations development requires pharmacokinetic drug-drug interaction (DDI) studies between active ingredients. For some drugs, pharmacokinetic properties such as long half-life or delayed distribution, make it difficult to conduct such clinical trials and to estimate the exact magnitud...

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Detalles Bibliográficos
Autores principales:	Hong, Yunjung, Jeon, Sangil, Choi, Suein, Han, Sungpil, Park, Maria, Han, Seunghoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Physiological Society and The Korean Society of Pharmacology 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552828/ https://www.ncbi.nlm.nih.gov/pubmed/34697265 http://dx.doi.org/10.4196/kjpp.2021.25.6.545

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