Cargando…

Peptide inhibition of acute lung injury in a novel two-hit rat model

Acute lung injury (ALI) often causes severe trauma that may progress to significant morbidity and mortality. ALI results from a combination of the underlying clinical condition of the patient (e.g., inflammation) with a secondary insult such as viral pneumonia or a blood transfusion. While the secon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sampson, Alana C., Lassiter, Brittany P., Gregory Rivera, Magdielis, Hair, Pamela S., Jackson, Kaitlyn G., Enos, Adrianne I., Vazifedan, Turaj, Werner, Alice L., Glesby, Marshall J., Lattanzio, Frank A., Cunnion, Kenji M., Krishna, Neel K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553074/ https://www.ncbi.nlm.nih.gov/pubmed/34710157 http://dx.doi.org/10.1371/journal.pone.0259133

Ejemplares similares

Incompatible erythrocyte transfusion with lipopolysaccharide induces acute lung injury in a novel rat model
por: Gregory Rivera, Magdielis, et al.
Publicado: (2020)

Peptide inhibition of neutrophil-mediated injury after in vivo challenge with supernatant of Pseudomonas aeruginosa and immune-complexes
por: Enos, Adrianne, et al.
Publicado: (2021)

Complement effectors, C5a and C3a, in cystic fibrosis lung fluid correlate with disease severity
por: Hair, Pamela S., et al.
Publicado: (2017)

Peptide Inhibitor of Complement C1 (PIC1) demonstrates antioxidant activity via single electron transport (SET) and hydrogen atom transfer (HAT)
por: Gregory Rivera, Magdielis, et al.
Publicado: (2018)

Inhibition of Immune Complex Complement Activation and Neutrophil Extracellular Trap Formation by Peptide Inhibitor of Complement C1
por: Hair, Pamela S., et al.
Publicado: (2018)

Inhibition of complement activation, myeloperoxidase, NET formation and oxidant activity by PIC1 peptide variants
por: Hair, Pamela S., et al.
Publicado: (2019)

Peptide Inhibitor of Complement C1 Inhibits the Peroxidase Activity of Hemoglobin and Myoglobin
por: Hair, Pamela S., et al.
Publicado: (2017)

Complement Activation and STAT4 Expression Are Associated with Early Inflammation in Diabetic Wounds
por: Cunnion, Kenji M., et al.
Publicado: (2017)

997. RLS-0071 Improves Survival in a Rat Model of Intestinal Necrosis
por: Cunnion, Kenji, et al.
Publicado: (2021)

Peptide Inhibitor of Complement C1, RLS-0071, Reduces Zosteriform Spread of Herpes Simplex Virus Type 1 Skin Infection and Promotes Survival in Infected Mice
por: Bhutta, Maimoona S., et al.
Publicado: (2021)

Classical complement pathway inhibition reduces brain damage in a hypoxic ischemic encephalopathy animal model
por: Kumar, Parvathi, et al.
Publicado: (2021)

Inhibition of Myeloperoxidase Activity in Cystic Fibrosis Sputum by Peptide Inhibitor of Complement C1 (PIC1)
por: Hair, Pamela S., et al.
Publicado: (2017)

Hyperglycemia Inhibits Complement-Mediated Immunological Control of S. aureus in a Rat Model of Peritonitis
por: Mauriello, Clifford T., et al.
Publicado: (2014)

Hyperglycemic conditions inhibit C3-mediated immunologic control of Staphylococcus aureus
por: Hair, Pamela S, et al.
Publicado: (2012)

Complement Effectors of Inflammation in Cystic Fibrosis Lung Fluid Correlate with Clinical Measures of Disease
por: Sass, Laura A., et al.
Publicado: (2015)

Changing temporal trends in patient volumes in a pediatric emergency department during a COVID-19 pandemic lockdown: A retrospective cohort study
por: Mullan, Paul C., et al.
Publicado: (2022)

Role of Molecular Diagnostics in the Management of Infectious Disease Emergencies
por: Krishna, Neel K., et al.
Publicado: (2012)

Clinical hypothermia temperatures increase complement activation and cell destruction via the classical pathway
por: Shah, Tushar A, et al.
Publicado: (2014)

Delayed Hemolytic Transfusion Reaction in a Patient With Sickle Cell Disease and the Role of the Classical Complement Pathway: A Case Report
por: Hair, Pamela S., et al.
Publicado: (2021)

Peptide Inhibitor of Complement C1, a Novel Suppressor of Classical Pathway Activation: Mechanistic Studies and Clinical Potential
por: Sharp, Julia A., et al.
Publicado: (2014)

Advancing Advocacy: Implementation of a Child Health Advocacy Curriculum in a Pediatrics Residency Program
por: Majeed, Amara, et al.
Publicado: (2020)

The EPICC Family of Anti-Inflammatory Peptides: Next Generation Peptides, Additional Mechanisms of Action, and In Vivo and Ex Vivo Efficacy
por: Krishna, Neel K., et al.
Publicado: (2022)

RLS-0071 Moderated Elevated Myeloperoxidase Level and Activity in an Asymptomatic Subject in Clinical Trial RLS-0071-101
por: Goss, Jessica M., et al.
Publicado: (2023)

Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats
por: Sharp, Julia A., et al.
Publicado: (2015)

Symptoms of Cerebrospinal Shunt Malfunction in Young Children: A National Caregiver Survey
por: Dorner, Rebecca A., et al.
Publicado: (2023)

Ceftriaxone-Induced Immune Hemolytic Anemia: In Vitro Reversal with Peptide Inhibitor of Complement C1 (PIC1)
por: Cunnion, Kenji M., et al.
Publicado: (2019)

Helping Mothers Survive: Program Evaluation and Early Outcomes of Maternal Care Training in the Dominican Republic
por: Smith, Meghan, et al.
Publicado: (2021)

Improvements to the HITS-CLIP protocol eliminate widespread mispriming artifacts
por: Gillen, Austin E., et al.
Publicado: (2016)

Implementation of an Intrahospital Transport Checklist for Emergency Department Admissions to Intensive Care
por: Venn, April M.-R., et al.
Publicado: (2021)

Hit Generation in TB Drug Discovery: From Genome to Granuloma
por: Yuan, Tianao, et al.
Publicado: (2018)

Staphylococcus aureus Surface Protein SdrE Binds Complement Regulator Factor H as an Immune Evasion Tactic
por: Sharp, Julia A., et al.
Publicado: (2012)

Revisiting the applicability of adult early post-operative nausea and vomiting risk factors for the paediatric patient: A prospective study using cotinine levels in children undergoing adenotonsillectomies
por: Chau, Destiny F, et al.
Publicado: (2017)

Correction to Hit Generation in TB Drug Discovery: From Genome to Granuloma
por: Yuan, Tianao, et al.
Publicado: (2019)

The two-hit theory hits 50
por: Chernoff, Jonathan
Publicado: (2021)

Acute MRSA Sinusitis with Intracranial Extension and Marginal Vancomycin Susceptibility
por: Kumar, Parvathi S., et al.
Publicado: (2013)

The two "hit" and multiple "hit" theories of carcinogenesis.
por: Ashley, D. J.
Publicado: (1969)

A Hit, a Hit—A Very Palpable Hit: Mild TBI and the Development of Epilepsy
por: Danzer, Steve C.
Publicado: (2019)

P1674: CLINICAL IMPACT OF NON-ADHERENCE TO HIT GUIDELINES: A DOUBLE HIT IN HIT
por: Al Raizah, A., et al.
Publicado: (2022)

1601 Screening for chronic obstructive pulmonary disease (COPD) in an urban HIV clinic
por: Shirley, Daniel, et al.
Publicado: (2014)

Greatest hits
Publicado: (1991)

Cannot write session to /tmp/vufind_sessions/sess_4mrhgjuun888lrq4onv9uc6a13