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Psychrobacter piechaudii shunt infection: first report of human infection

Psychrobacter piechaudii is a recently described species of Gram-negative bacteria in the Moraxellaceae family. No cases of human infection due to this species have been described before. We report the case of an ex-premature infant girl with hydrocephalus secondary to intraventricular haemorrhage w...

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Autores principales: Kumaria, Ashwin, Crusz, Shanika A., Lister, Michelle, Kirkman, Matthew A., Macarthur, Donald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553102/
https://www.ncbi.nlm.nih.gov/pubmed/34713345
http://dx.doi.org/10.1007/s00381-021-05401-7
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author Kumaria, Ashwin
Crusz, Shanika A.
Lister, Michelle
Kirkman, Matthew A.
Macarthur, Donald C.
author_facet Kumaria, Ashwin
Crusz, Shanika A.
Lister, Michelle
Kirkman, Matthew A.
Macarthur, Donald C.
author_sort Kumaria, Ashwin
collection PubMed
description Psychrobacter piechaudii is a recently described species of Gram-negative bacteria in the Moraxellaceae family. No cases of human infection due to this species have been described before. We report the case of an ex-premature infant girl with hydrocephalus secondary to intraventricular haemorrhage who underwent multiple cerebrospinal fluid (CSF) shunt operations. She ultimately developed Psychrobacter piechaudii meningitis, presenting as ventriculoperitoneal shunt dysfunction and wound leak, which necessitated removal of the shunt, a period of external ventricular drainage and antibiotics. We found this organism to be sensitive to intravenous ceftazidime (50 mg/kg) and ciprofloxacin, and a 7–10 day treatment course prior to shunt re-insertion (and 3 week total course) was sufficient. The patient is well post-operatively. To the best of our knowledge, this is the first reported case of Psychrobacter piechaudii infection in a human.
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spelling pubmed-85531022021-10-29 Psychrobacter piechaudii shunt infection: first report of human infection Kumaria, Ashwin Crusz, Shanika A. Lister, Michelle Kirkman, Matthew A. Macarthur, Donald C. Childs Nerv Syst Case Report Psychrobacter piechaudii is a recently described species of Gram-negative bacteria in the Moraxellaceae family. No cases of human infection due to this species have been described before. We report the case of an ex-premature infant girl with hydrocephalus secondary to intraventricular haemorrhage who underwent multiple cerebrospinal fluid (CSF) shunt operations. She ultimately developed Psychrobacter piechaudii meningitis, presenting as ventriculoperitoneal shunt dysfunction and wound leak, which necessitated removal of the shunt, a period of external ventricular drainage and antibiotics. We found this organism to be sensitive to intravenous ceftazidime (50 mg/kg) and ciprofloxacin, and a 7–10 day treatment course prior to shunt re-insertion (and 3 week total course) was sufficient. The patient is well post-operatively. To the best of our knowledge, this is the first reported case of Psychrobacter piechaudii infection in a human. Springer Berlin Heidelberg 2021-10-28 2022 /pmc/articles/PMC8553102/ /pubmed/34713345 http://dx.doi.org/10.1007/s00381-021-05401-7 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Case Report
Kumaria, Ashwin
Crusz, Shanika A.
Lister, Michelle
Kirkman, Matthew A.
Macarthur, Donald C.
Psychrobacter piechaudii shunt infection: first report of human infection
title Psychrobacter piechaudii shunt infection: first report of human infection
title_full Psychrobacter piechaudii shunt infection: first report of human infection
title_fullStr Psychrobacter piechaudii shunt infection: first report of human infection
title_full_unstemmed Psychrobacter piechaudii shunt infection: first report of human infection
title_short Psychrobacter piechaudii shunt infection: first report of human infection
title_sort psychrobacter piechaudii shunt infection: first report of human infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553102/
https://www.ncbi.nlm.nih.gov/pubmed/34713345
http://dx.doi.org/10.1007/s00381-021-05401-7
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