Mitochondrial respiratory chain and Krebs cycle enzyme function in human donor livers subjected to end-ischaemic hypothermic machine perfusion

INTRODUCTION: Marginal human donor livers are highly susceptible to ischaemia reperfusion injury and mitochondrial dysfunction. Oxygenation during hypothermic machine perfusion (HMP) was proposed to protect the mitochondria but the mechanism is unclear. Additionally, the distribution and uptake of p...

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Detalles Bibliográficos
Autores principales: Abudhaise, Hamid, Taanman, Jan-Willem, DeMuylder, Peter, Fuller, Barry, Davidson, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553115/
https://www.ncbi.nlm.nih.gov/pubmed/34710117
http://dx.doi.org/10.1371/journal.pone.0257783

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