IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay

Regnase-1 is an endoribonuclease crucial for controlling inflammation by degrading mRNAs encoding cytokines and inflammatory mediators in mammals. However, it is unclear how Regnase-1-mediated mRNA decay is controlled in interleukin (IL)-1β- or Toll-like receptor (TLR) ligand-stimulated cells. Here,...

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Detalles Bibliográficos
Autores principales: Akaki, Kotaro, Ogata, Kosuke, Yamauchi, Yuhei, Iwai, Noriki, Tse, Ka Man, Hia, Fabian, Mochizuki, Atsushi, Ishihama, Yasushi, Mino, Takashi, Takeuchi, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553338/
https://www.ncbi.nlm.nih.gov/pubmed/34636324
http://dx.doi.org/10.7554/eLife.71966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553338/
https://www.ncbi.nlm.nih.gov/pubmed/34636324
http://dx.doi.org/10.7554/eLife.71966

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