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IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay

Regnase-1 is an endoribonuclease crucial for controlling inflammation by degrading mRNAs encoding cytokines and inflammatory mediators in mammals. However, it is unclear how Regnase-1-mediated mRNA decay is controlled in interleukin (IL)-1β- or Toll-like receptor (TLR) ligand-stimulated cells. Here,...

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Detalles Bibliográficos
Autores principales:	Akaki, Kotaro, Ogata, Kosuke, Yamauchi, Yuhei, Iwai, Noriki, Tse, Ka Man, Hia, Fabian, Mochizuki, Atsushi, Ishihama, Yasushi, Mino, Takashi, Takeuchi, Osamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553338/ https://www.ncbi.nlm.nih.gov/pubmed/34636324 http://dx.doi.org/10.7554/eLife.71966

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