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Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia
BACKGROUND: Decidualization of the uterine mucosa drives the maternal adaptation to invasion by the placenta. Appropriate depth of placental invasion is needed to support a healthy pregnancy; shallow invasion is associated with the development of severe preeclampsia (sPE). Maternal contribution to s...
Autores principales: | Garrido-Gomez, Tamara, Castillo-Marco, Nerea, Clemente-Ciscar, Mónica, Cordero, Teresa, Muñoz-Blat, Irene, Amadoz, Alicia, Jimenez-Almazan, Jorge, Monfort-Ortiz, Rogelio, Climent, Reyes, Perales-Marin, Alfredo, Simon, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553341/ https://www.ncbi.nlm.nih.gov/pubmed/34709177 http://dx.doi.org/10.7554/eLife.70753 |
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