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A Case of Autosomal Recessive Interferon Alpha/Beta Receptor Alpha Chain (IFNAR1) Deficiency with Severe COVID-19

BACKGROUND: Interferons (IFNs) play a crucial role in antiviral immunity. Genetic defects in interferon receptors, IFNs, and auto-antibodies against IFNs can lead to the development of life-threatening forms of infectious diseases like a severe form of COVID-19. CASE PRESENTATION: A 13-year-old boy...

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Detalles Bibliográficos
Autores principales: Khanmohammadi, Shaghayegh, Rezaei, Nima, Khazaei, Mehdi, Shirkani, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553400/
https://www.ncbi.nlm.nih.gov/pubmed/34713375
http://dx.doi.org/10.1007/s10875-021-01166-5