Cargando…

A Mathematical Method to Adjust MLC Leaf End Position for Accurate Dose Calculation in Carbon Ion Beam Radiation Therapy Treatment Planning System

INTRODUCTION: We present a mathematical method to adjust the leaf end position for dose calculation correction in the carbon ion radiation therapy treatment planning system. METHODS AND MATERIALS: A straggling range algorism of 400 MeV/n carbon ion beam in nine different multileaf collimator (MLC) m...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yan-Shan, Ye, Yan-Cheng, Wu, Jia-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553445/
https://www.ncbi.nlm.nih.gov/pubmed/34722768
http://dx.doi.org/10.1155/2021/6762724
_version_ 1784591584367476736
author Zhang, Yan-Shan
Ye, Yan-Cheng
Wu, Jia-Ming
author_facet Zhang, Yan-Shan
Ye, Yan-Cheng
Wu, Jia-Ming
author_sort Zhang, Yan-Shan
collection PubMed
description INTRODUCTION: We present a mathematical method to adjust the leaf end position for dose calculation correction in the carbon ion radiation therapy treatment planning system. METHODS AND MATERIALS: A straggling range algorism of 400 MeV/n carbon ion beam in nine different multileaf collimator (MLC) materials was conducted to calculate the dose 50% point to derive the offset corrections in the carbon ion treatment planning system (ciPlan). The visualized light field edge position in the treatment planning system is denoted as X(tang.p), and MLC position (X(mlc.p)) is defined as the source to leaf end midpoint projection on axis for monitor unit calculation. The virtual source position of energy at 400 MeV/n and straggling range in MLC at different field sizes were used to calculate the dose 50% position on axis. On-axis MLC offset (correction) could then be obtained from the position corresponding to 50% of the central axis dose minus the X(mlc.p). RESULTS: The exact MLC position in the carbon ion treatment planning system can be used as an offset to do the correction. The offset correction of pure tungsten is the smallest among the others due to its shortest straggling range of carbon ion beam in MLC. The positions of 50% dose of all MLC materials are always located in between X(tang.p) and X(mlc.p) under the largest field of 12 cm by 12 cm. CONCLUSIONS: MLC offset should be adjusted carefully at different field sizes in the treatment planning systems especially of its small penumbra characteristic in the carbon ion beam. It is necessary to find out the dose 50% position for adjusting MLC leaf edge on-axis location in the treatment planning system to reduce dose calculation error.
format Online
Article
Text
id pubmed-8553445
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-85534452021-10-29 A Mathematical Method to Adjust MLC Leaf End Position for Accurate Dose Calculation in Carbon Ion Beam Radiation Therapy Treatment Planning System Zhang, Yan-Shan Ye, Yan-Cheng Wu, Jia-Ming Biomed Res Int Research Article INTRODUCTION: We present a mathematical method to adjust the leaf end position for dose calculation correction in the carbon ion radiation therapy treatment planning system. METHODS AND MATERIALS: A straggling range algorism of 400 MeV/n carbon ion beam in nine different multileaf collimator (MLC) materials was conducted to calculate the dose 50% point to derive the offset corrections in the carbon ion treatment planning system (ciPlan). The visualized light field edge position in the treatment planning system is denoted as X(tang.p), and MLC position (X(mlc.p)) is defined as the source to leaf end midpoint projection on axis for monitor unit calculation. The virtual source position of energy at 400 MeV/n and straggling range in MLC at different field sizes were used to calculate the dose 50% position on axis. On-axis MLC offset (correction) could then be obtained from the position corresponding to 50% of the central axis dose minus the X(mlc.p). RESULTS: The exact MLC position in the carbon ion treatment planning system can be used as an offset to do the correction. The offset correction of pure tungsten is the smallest among the others due to its shortest straggling range of carbon ion beam in MLC. The positions of 50% dose of all MLC materials are always located in between X(tang.p) and X(mlc.p) under the largest field of 12 cm by 12 cm. CONCLUSIONS: MLC offset should be adjusted carefully at different field sizes in the treatment planning systems especially of its small penumbra characteristic in the carbon ion beam. It is necessary to find out the dose 50% position for adjusting MLC leaf edge on-axis location in the treatment planning system to reduce dose calculation error. Hindawi 2021-10-21 /pmc/articles/PMC8553445/ /pubmed/34722768 http://dx.doi.org/10.1155/2021/6762724 Text en Copyright © 2021 Yan-Shan Zhang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Yan-Shan
Ye, Yan-Cheng
Wu, Jia-Ming
A Mathematical Method to Adjust MLC Leaf End Position for Accurate Dose Calculation in Carbon Ion Beam Radiation Therapy Treatment Planning System
title A Mathematical Method to Adjust MLC Leaf End Position for Accurate Dose Calculation in Carbon Ion Beam Radiation Therapy Treatment Planning System
title_full A Mathematical Method to Adjust MLC Leaf End Position for Accurate Dose Calculation in Carbon Ion Beam Radiation Therapy Treatment Planning System
title_fullStr A Mathematical Method to Adjust MLC Leaf End Position for Accurate Dose Calculation in Carbon Ion Beam Radiation Therapy Treatment Planning System
title_full_unstemmed A Mathematical Method to Adjust MLC Leaf End Position for Accurate Dose Calculation in Carbon Ion Beam Radiation Therapy Treatment Planning System
title_short A Mathematical Method to Adjust MLC Leaf End Position for Accurate Dose Calculation in Carbon Ion Beam Radiation Therapy Treatment Planning System
title_sort mathematical method to adjust mlc leaf end position for accurate dose calculation in carbon ion beam radiation therapy treatment planning system
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553445/
https://www.ncbi.nlm.nih.gov/pubmed/34722768
http://dx.doi.org/10.1155/2021/6762724
work_keys_str_mv AT zhangyanshan amathematicalmethodtoadjustmlcleafendpositionforaccuratedosecalculationincarbonionbeamradiationtherapytreatmentplanningsystem
AT yeyancheng amathematicalmethodtoadjustmlcleafendpositionforaccuratedosecalculationincarbonionbeamradiationtherapytreatmentplanningsystem
AT wujiaming amathematicalmethodtoadjustmlcleafendpositionforaccuratedosecalculationincarbonionbeamradiationtherapytreatmentplanningsystem
AT zhangyanshan mathematicalmethodtoadjustmlcleafendpositionforaccuratedosecalculationincarbonionbeamradiationtherapytreatmentplanningsystem
AT yeyancheng mathematicalmethodtoadjustmlcleafendpositionforaccuratedosecalculationincarbonionbeamradiationtherapytreatmentplanningsystem
AT wujiaming mathematicalmethodtoadjustmlcleafendpositionforaccuratedosecalculationincarbonionbeamradiationtherapytreatmentplanningsystem