Cargando…

Exploring the Effect of Dapagliflozin on Alcoholic Kidney Injury and Renal Interstitial Fibrosis in Rats Based on TIMP-1/MMP-24 Pathway

OBJECTIVE: To establish a rat model of alcoholic kidney injury and detect the expression of TIMP-1/MMP-24 in the kidneys of rats with alcoholic kidney injury at the molecular pathological level, so as to explore the mechanism of alcohol abuse leading to kidney injury and renal interstitial fibrosis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yundou, Song, Peijun, Yuan, Xinke, Li, Dayong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553464/ https://www.ncbi.nlm.nih.gov/pubmed/34721639 http://dx.doi.org/10.1155/2021/6538189

Ejemplares similares

Retracted: Exploring the Effect of Dapagliflozin on Alcoholic Kidney Injury and Renal Interstitial Fibrosis in Rats Based on TIMP-1/MMP-24 Pathway
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Expression and Roles of MMP-2, MMP-9, MMP-13, TIMP-1, and TIMP-2 in Allergic Nasal Mucosa
por: Mori, Sachiko, et al.
Publicado: (2012)

Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas
por: Meneses-García, Abelardo, et al.
Publicado: (2008)

Evaluation of MMP-9 and MMP-2 and their suppressor TIMP-1 and TIMP-2 in adenocarcinoma of esophagogastric junction
por: Lu, Xiaofei, et al.
Publicado: (2016)

Disparate effects of MMP and TIMP modulation on coronary atherosclerosis and associated myocardial fibrosis
por: Kremastiotis, Georgios, et al.
Publicado: (2021)

Expressions of Matrix Metalloproteinases (MMP-2, MMP-7, and MMP-9) and Their Inhibitors (TIMP-1, TIMP-2) in Inflammatory Bowel Diseases
por: Jakubowska, Katarzyna, et al.
Publicado: (2016)

MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differentiated Thyroid Carcinoma
por: Zhang, Wen-jing, et al.
Publicado: (2019)

The usefulness of MMP-9, TIMP-1 and MMP-9/TIMP-1 ratio for diagnosis and assessment of COPD severity
por: Dimic-Janjic, Sanja, et al.
Publicado: (2023)

MMP-2 and MMP-9 Activities and TIMP-1 and TIMP-2 Expression in the Prostatic Tissue of Two Ethanol-Preferring Rat Models
por: Fioruci-Fontanelli, Beatriz Aparecida, et al.
Publicado: (2015)

RORA alleviates LPS-induced apoptosis of renal epithelial cells by promoting PGC-1α transcription
por: Li, Dayong, et al.
Publicado: (2022)

MMP-9 and MMP-2 gelatinases and TIMP-1 and TIMP-2 inhibitors in breast cancer: correlations with prognostic factors
por: Jinga, D C, et al.
Publicado: (2006)

MMP-2 and TIMP-2 in Patients with Heart Failure and Chronic Kidney Disease
por: Kobusiak-Prokopowicz, Malgorzata, et al.
Publicado: (2018)

Diagnostic values of MMP-7, MMP-9, MMP-11, TIMP-1, TIMP-2, CEA, and CA19-9 in patients with colorectal cancer
por: Huang, Xiwen, et al.
Publicado: (2021)

Plasma Glycosaminoglycan Profiles in Systemic Sclerosis: Associations with MMP-3, MMP-10, TIMP-1, TIMP-2, and TGF-Beta
por: Kuźnik-Trocha, Kornelia, et al.
Publicado: (2020)

TIMP-1, TIMP-2 and MMP-9 as prognostic markers for clinical outcome in sepsis
por: Hoffmann, U, et al.
Publicado: (2003)

Assessment of RANTES, MIP4A, MMP7, MMP9, MMP14, TIMP 1, TIMP 2 and TIMP 3 concentration in the follicular fluid of patients undergoing in vitro fertilization/embryo transfer procedure
por: Adamczak, Rafał, et al.
Publicado: (2023)

Upregulation and differential expression of matrilysin (MMP-7) and metalloelastase (MMP-12) and their inhibitors TIMP-1 and TIMP-3 in Barrett's oesophageal adenocarcinoma
por: Salmela, M T, et al.
Publicado: (2001)

The Imbalance of MMP-2/TIMP-2 and MMP-9/TIMP-1 Contributes to Collagen Deposition Disorder in Diabetic Non-Injured Skin
por: Zhou, Peng, et al.
Publicado: (2021)

Matrix metalloproteinase MMP-8, TIMP-1 and MMP-8/TIMP-1 ratio in plasma in methicillin-sensitive Staphylococcus aureus bacteremia
por: Forsblom, Erik, et al.
Publicado: (2021)

Effect of silibinin on the expression of MMP2, MMP3, MMP9 and TIMP2 in kidney and lung after hepatic ischemia/reperfusion injury in an experimental rat model
por: Kollaras, Vasileios, et al.
Publicado: (2021)

The Activity of Matrix Metalloproteinases (MMP-2, MMP-9) and Their Tissue Inhibitors (TIMP-1, TIMP-3) in the Cerebral Cortex and Hippocampus in Experimental Acanthamoebiasis
por: Łanocha-Arendarczyk, Natalia, et al.
Publicado: (2018)

Matrix stiffness modulates the activity of MMP-9 and TIMP-1 in hepatic stellate cells to perpetuate fibrosis
por: Lachowski, Dariusz, et al.
Publicado: (2019)

Mechanisims of asthma and allergic disease – 1077. Differential expression and roles oF MMP-2, MMP-9, MMP-13, TIMP-1, and TIMP-2 in allergic rhinitis
por: Mori, Sachiko, et al.
Publicado: (2013)

The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis
por: Têtu, Bernard, et al.
Publicado: (2006)

Assessment of MMP-1, MMP-8 and TIMP-2 in experimental periodontitis treated with kaempferol
por: Balli, Umut, et al.
Publicado: (2016)

Regulation of MT1-MMP/MMP-2/TIMP-2 axis in human placenta
por: Vincent, Zoë L, et al.
Publicado: (2015)

Levels of Circulating TIMP-2 and MMP2-TIMP2 Complex Are Decreased in Squamous Cervical Carcinoma
por: Anne, Talvensaari-Mattila, et al.
Publicado: (2010)

Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis
por: Azevedo Martins, Jordana Maria, et al.
Publicado: (2020)

Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer
por: Kubben, F J G M, et al.
Publicado: (2006)

Expression of MMP-2 and TIMP-1 in Renal Tissue of Patients with Chronic Active Antibody-mediated Renal Graft Rejection
por: Yan, Qiang, et al.
Publicado: (2012)

Renal Fibrosis mRNA Classifier: Validation in Experimental Lithium-Induced Interstitial Fibrosis in the Rat Kidney
por: Marti, Hans-Peter, et al.
Publicado: (2016)

The increased of MMP-9 and MMP-2 with the decreased of TIMP-1 on the uterosacral ligament after childbirth
por: Rahajeng, Rahajeng
Publicado: (2018)

Increase in Serum MMP-9 and TIMP-1 Concentrations during Alcohol Intoxication in Adolescents—A Preliminary Study
por: Zdanowicz, Katarzyna, et al.
Publicado: (2022)

Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis
por: Cheng, Zhengyuan, et al.
Publicado: (2018)

Dapagliflozin can alleviate renal fibrosis in rats with streptozotocin‑induced type 2 diabetes mellitus
por: Xue, Song, et al.
Publicado: (2023)

A Novel Cell Line Derived from Pleomorphic Adenoma Expresses MMP2, MMP9, TIMP1, TIMP2, and Shows Numeric Chromosomal Anomalies
por: Falcão, Aline Semblano Carreira, et al.
Publicado: (2014)

TIMP1 and MMP9 are predictors of mortality in septic patients in the emergency department and intensive care unit unlike MMP9/TIMP1 ratio: Multivariate model
por: Niño, Maria Eugenia, et al.
Publicado: (2017)

Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14
por: Hayun, Hezi, et al.
Publicado: (2023)

Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14
por: Hayun, Hezi, et al.
Publicado: (2023)

The selected genetic polymorphisms of metalloproteinases MMP2, 7, 9 and MMP inhibitor TIMP2 in sarcoidosis
por: Piotrowski, Wojciech J., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ienhnljub6e2hln1mh3ukdihg2