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A Variant of sNASP Exacerbates Lymphocyte Subset Disorder and Nephritis in a Spontaneous Lupus Model Sle1.Yaa Mouse
A variant of somatic nuclear autoantigenic sperm protein (sNASP) was identified from the murine lupus susceptibility locus Sle2c1 by whole exome sequencing (WES). Previous studies have shown that mutant sNASP could synergize with the Fas(lpr) mutation in exacerbating autoimmunity and aggravating end...
Autores principales: | Zhang, Jianye, Du, Xiaoping, Wang, Hui, Bao, Yatao, Lian, Meng, Xu, Zhiwei, Ju, Jiyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553485/ https://www.ncbi.nlm.nih.gov/pubmed/34720750 http://dx.doi.org/10.1155/2021/8175863 |
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