Dauer Development Modulates Olfactory Behavior

Reproductive adults and developmentally arrested larvae often occupy different ecological niches and thus are expected to respond differently to environmental stimuli. To understand the genes that coordinate dauer development and olfactory behavior, we examined adult and dauer C. elegans in wild-typ...

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Detalles Bibliográficos
Autores principales: Vertiz, Johnny, Carstensen, Heather, Hong, Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553572/
https://www.ncbi.nlm.nih.gov/pubmed/34723151
http://dx.doi.org/10.17912/micropub.biology.000479
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author Vertiz, Johnny
Carstensen, Heather
Hong, Ray
author_facet Vertiz, Johnny
Carstensen, Heather
Hong, Ray
author_sort Vertiz, Johnny
collection PubMed
description Reproductive adults and developmentally arrested larvae often occupy different ecological niches and thus are expected to respond differently to environmental stimuli. To understand the genes that coordinate dauer development and olfactory behavior, we examined adult and dauer C. elegans in wild-type and dauer constitutive mutants (Daf-c). We found all dauers showed decreased attraction to all three odorants tested compared to adults, with daf-7 dauer larva (DL) exhibiting a concentration-dependent preference shift towards isoamyl alcohol, suggesting that the TGF-ß pathway is involved in both dauer regulation and dauer-specific odortaxis.
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spelling pubmed-85535722021-10-29 Dauer Development Modulates Olfactory Behavior Vertiz, Johnny Carstensen, Heather Hong, Ray MicroPubl Biol New Finding Reproductive adults and developmentally arrested larvae often occupy different ecological niches and thus are expected to respond differently to environmental stimuli. To understand the genes that coordinate dauer development and olfactory behavior, we examined adult and dauer C. elegans in wild-type and dauer constitutive mutants (Daf-c). We found all dauers showed decreased attraction to all three odorants tested compared to adults, with daf-7 dauer larva (DL) exhibiting a concentration-dependent preference shift towards isoamyl alcohol, suggesting that the TGF-ß pathway is involved in both dauer regulation and dauer-specific odortaxis. Caltech Library 2021-10-14 /pmc/articles/PMC8553572/ /pubmed/34723151 http://dx.doi.org/10.17912/micropub.biology.000479 Text en Copyright: © 2021 by the authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle New Finding
Vertiz, Johnny
Carstensen, Heather
Hong, Ray
Dauer Development Modulates Olfactory Behavior
title Dauer Development Modulates Olfactory Behavior
title_full Dauer Development Modulates Olfactory Behavior
title_fullStr Dauer Development Modulates Olfactory Behavior
title_full_unstemmed Dauer Development Modulates Olfactory Behavior
title_short Dauer Development Modulates Olfactory Behavior
title_sort dauer development modulates olfactory behavior
topic New Finding
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553572/
https://www.ncbi.nlm.nih.gov/pubmed/34723151
http://dx.doi.org/10.17912/micropub.biology.000479
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