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MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3

MAP4K4 is a Ste20 member and reported to play important roles in various pathologies, including in cancer. However, the mechanism by which MAP4K4 promotes pancreatic cancer is not fully understood. It is suggested that MAP4K4 might function as a cancer promoter via specific downstream target(s) in a...

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Detalles Bibliográficos
Autores principales:	Singh, Sunil Kumar, Kumar, Sandeep, Viswakarma, Navin, Principe, Daniel R., Das, Subhasis, Sondarva, Gautam, Nair, Rakesh Sathish, Srivastava, Piush, Sinha, Subhash C., Grippo, Paul J., Thatcher, Gregory R. J., Rana, Basabi, Rana, Ajay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553609/ https://www.ncbi.nlm.nih.gov/pubmed/34511598 http://dx.doi.org/10.1038/s41388-021-02007-w

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