Germline ATM variants predispose to melanoma: a joint analysis across the GenoMEL and MelaNostrum consortia

PURPOSE: Ataxia–Telangiectasia Mutated (ATM) has been implicated in the risk of several cancers, but establishing a causal relationship is often challenging. Although ATM single-nucleotide polymorphisms have been linked to melanoma, few functional alleles have been identified. Therefore, ATM impact...

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Detalles Bibliográficos
Autores principales: Dalmasso, B., Pastorino, L., Nathan, V., Shah, N. N., Palmer, J. M., Howlie, M., Johansson, P. A., Freedman, N. D., Carter, B. D., Beane-Freeman, L., Hicks, B., Molven, A., Helgadottir, H., Sankar, A., Tsao, H., Stratigos, A. J., Helsing, P., Van Doorn, R., Gruis, N. A., Visser, M., Wadt, K. A. W., Mann, G., Holland, E. A., Nagore, E., Potrony, M., Puig, S., Menin, C., Peris, K., Fargnoli, M. C., Calista, D., Soufir, N., Harland, M., Bishop, T., Kanetsky, P. A., Elder, D. E., Andreotti, V., Vanni, I., Bruno, W., Höiom, V., Tucker, M. A., Yang, X. R., Andresen, P. A., Adams, D. J., Landi, M. T., Hayward, N. K., Goldstein, A. M., Ghiorzo, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553617/
https://www.ncbi.nlm.nih.gov/pubmed/34262154
http://dx.doi.org/10.1038/s41436-021-01240-8

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