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Factors contributing to clinically important health utility gains in cochlear implant recipients

PURPOSE: Cochlear implantation can restore access to sound and speech understanding in subjects with substantial hearing loss. The Health Utilities Index Mark III (HUI3) measures the impact of an intervention on the patient’s quality of life and is sensitive to changes in hearing. In the current stu...

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Autores principales: Müller, Lida, Graham, Petra, Kaur, Jasmin, Wyss, Josie, Greenham, Paula, James, Chris J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553698/
https://www.ncbi.nlm.nih.gov/pubmed/33452623
http://dx.doi.org/10.1007/s00405-020-06589-1
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author Müller, Lida
Graham, Petra
Kaur, Jasmin
Wyss, Josie
Greenham, Paula
James, Chris J.
author_facet Müller, Lida
Graham, Petra
Kaur, Jasmin
Wyss, Josie
Greenham, Paula
James, Chris J.
author_sort Müller, Lida
collection PubMed
description PURPOSE: Cochlear implantation can restore access to sound and speech understanding in subjects with substantial hearing loss. The Health Utilities Index Mark III (HUI3) measures the impact of an intervention on the patient’s quality of life and is sensitive to changes in hearing. In the current study we used factor analysis to predict a clinically important gain in HUI3 scores in adult cochlear implant recipients. METHODS: Data were collected in an observational study for 137 adult recipients from a single center who had at least 1-year HUI3 follow-up. Demographic and other baseline parameters were retrospectively analyzed for their association with a clinically important HUI3 scale gain, defined as at least 0.1 points. Data were also collected for the speech spatial qualities (SSQ) scale. RESULTS: Baseline telephone use and HUI3 hearing, speech and emotion attribute levels were significantly associated with clinically important gains in HUI3 scores. However, SSQ scores increased significantly with or without clinically important HUI3 gains. CONCLUSION: Those subjects who were unhappy or experienced difficulties communicating with strangers or in a group were twice as likely to obtain a clinically important gain in health utility compared to those who were happy or had less difficulty communicating. Subjects who were unable to use the telephone prior to cochlear implantation were one and a half times more likely to obtain a clinically important gain. The SSQ scale was more sensitive to hearing improvements due to cochlear implantation. An inability to use the telephone is an easy to assess biomarker for candidacy for cochlear implantation.
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spelling pubmed-85536982021-11-04 Factors contributing to clinically important health utility gains in cochlear implant recipients Müller, Lida Graham, Petra Kaur, Jasmin Wyss, Josie Greenham, Paula James, Chris J. Eur Arch Otorhinolaryngol Otology PURPOSE: Cochlear implantation can restore access to sound and speech understanding in subjects with substantial hearing loss. The Health Utilities Index Mark III (HUI3) measures the impact of an intervention on the patient’s quality of life and is sensitive to changes in hearing. In the current study we used factor analysis to predict a clinically important gain in HUI3 scores in adult cochlear implant recipients. METHODS: Data were collected in an observational study for 137 adult recipients from a single center who had at least 1-year HUI3 follow-up. Demographic and other baseline parameters were retrospectively analyzed for their association with a clinically important HUI3 scale gain, defined as at least 0.1 points. Data were also collected for the speech spatial qualities (SSQ) scale. RESULTS: Baseline telephone use and HUI3 hearing, speech and emotion attribute levels were significantly associated with clinically important gains in HUI3 scores. However, SSQ scores increased significantly with or without clinically important HUI3 gains. CONCLUSION: Those subjects who were unhappy or experienced difficulties communicating with strangers or in a group were twice as likely to obtain a clinically important gain in health utility compared to those who were happy or had less difficulty communicating. Subjects who were unable to use the telephone prior to cochlear implantation were one and a half times more likely to obtain a clinically important gain. The SSQ scale was more sensitive to hearing improvements due to cochlear implantation. An inability to use the telephone is an easy to assess biomarker for candidacy for cochlear implantation. Springer Berlin Heidelberg 2021-01-15 2021 /pmc/articles/PMC8553698/ /pubmed/33452623 http://dx.doi.org/10.1007/s00405-020-06589-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Otology
Müller, Lida
Graham, Petra
Kaur, Jasmin
Wyss, Josie
Greenham, Paula
James, Chris J.
Factors contributing to clinically important health utility gains in cochlear implant recipients
title Factors contributing to clinically important health utility gains in cochlear implant recipients
title_full Factors contributing to clinically important health utility gains in cochlear implant recipients
title_fullStr Factors contributing to clinically important health utility gains in cochlear implant recipients
title_full_unstemmed Factors contributing to clinically important health utility gains in cochlear implant recipients
title_short Factors contributing to clinically important health utility gains in cochlear implant recipients
title_sort factors contributing to clinically important health utility gains in cochlear implant recipients
topic Otology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553698/
https://www.ncbi.nlm.nih.gov/pubmed/33452623
http://dx.doi.org/10.1007/s00405-020-06589-1
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