Changes in H(+), K(+), and Ca(2+) Concentrations, as Observed in Seizures, Induce Action Potential Signaling in Cortical Neurons by a Mechanism That Depends Partially on Acid-Sensing Ion Channels

Acid-sensing ion channels (ASICs) are activated by extracellular acidification. Because ASIC currents are transient, these channels appear to be ideal sensors for detecting the onset of rapid pH changes. ASICs are involved in neuronal death after ischemic stroke, and in the sensation of inflammatory...

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Detalles Bibliográficos
Autores principales: Alijevic, Omar, Peng, Zhong, Kellenberger, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553998/
https://www.ncbi.nlm.nih.gov/pubmed/34720879
http://dx.doi.org/10.3389/fncel.2021.732869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553998/
https://www.ncbi.nlm.nih.gov/pubmed/34720879
http://dx.doi.org/10.3389/fncel.2021.732869

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