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Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554009/ https://www.ncbi.nlm.nih.gov/pubmed/34729348 http://dx.doi.org/10.1016/j.epsc.2021.102103 |
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author | Wintler, Taylor Zherebtsov, Monica Carmack, Susanne Muntean, Rebecca Hill, Sarah J. |
author_facet | Wintler, Taylor Zherebtsov, Monica Carmack, Susanne Muntean, Rebecca Hill, Sarah J. |
author_sort | Wintler, Taylor |
collection | PubMed |
description | We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and rectum requiring surgical debridement and diverting colostomy. As a part of her work-up, she tested positive for COVID-19 total IgG/IgM antibodies and ANCA antibodies. This case complements previously reported cases of COVID-19 induced autoimmune disease in children but is novel in describing extensive intestinal disease as a result of an autoimmune vasculitis in a child. |
format | Online Article Text |
id | pubmed-8554009 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Authors. Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85540092021-10-29 Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager Wintler, Taylor Zherebtsov, Monica Carmack, Susanne Muntean, Rebecca Hill, Sarah J. J Pediatr Surg Case Rep Article We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and rectum requiring surgical debridement and diverting colostomy. As a part of her work-up, she tested positive for COVID-19 total IgG/IgM antibodies and ANCA antibodies. This case complements previously reported cases of COVID-19 induced autoimmune disease in children but is novel in describing extensive intestinal disease as a result of an autoimmune vasculitis in a child. The Authors. Published by Elsevier Inc. 2021-12 2021-10-29 /pmc/articles/PMC8554009/ /pubmed/34729348 http://dx.doi.org/10.1016/j.epsc.2021.102103 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Wintler, Taylor Zherebtsov, Monica Carmack, Susanne Muntean, Rebecca Hill, Sarah J. Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager |
title | Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager |
title_full | Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager |
title_fullStr | Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager |
title_full_unstemmed | Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager |
title_short | Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager |
title_sort | acute pr3-anca vasculitis in an asymptomatic covid-19 teenager |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554009/ https://www.ncbi.nlm.nih.gov/pubmed/34729348 http://dx.doi.org/10.1016/j.epsc.2021.102103 |
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