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Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager

We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and...

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Autores principales: Wintler, Taylor, Zherebtsov, Monica, Carmack, Susanne, Muntean, Rebecca, Hill, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554009/
https://www.ncbi.nlm.nih.gov/pubmed/34729348
http://dx.doi.org/10.1016/j.epsc.2021.102103
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author Wintler, Taylor
Zherebtsov, Monica
Carmack, Susanne
Muntean, Rebecca
Hill, Sarah J.
author_facet Wintler, Taylor
Zherebtsov, Monica
Carmack, Susanne
Muntean, Rebecca
Hill, Sarah J.
author_sort Wintler, Taylor
collection PubMed
description We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and rectum requiring surgical debridement and diverting colostomy. As a part of her work-up, she tested positive for COVID-19 total IgG/IgM antibodies and ANCA antibodies. This case complements previously reported cases of COVID-19 induced autoimmune disease in children but is novel in describing extensive intestinal disease as a result of an autoimmune vasculitis in a child.
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spelling pubmed-85540092021-10-29 Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager Wintler, Taylor Zherebtsov, Monica Carmack, Susanne Muntean, Rebecca Hill, Sarah J. J Pediatr Surg Case Rep Article We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and rectum requiring surgical debridement and diverting colostomy. As a part of her work-up, she tested positive for COVID-19 total IgG/IgM antibodies and ANCA antibodies. This case complements previously reported cases of COVID-19 induced autoimmune disease in children but is novel in describing extensive intestinal disease as a result of an autoimmune vasculitis in a child. The Authors. Published by Elsevier Inc. 2021-12 2021-10-29 /pmc/articles/PMC8554009/ /pubmed/34729348 http://dx.doi.org/10.1016/j.epsc.2021.102103 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Wintler, Taylor
Zherebtsov, Monica
Carmack, Susanne
Muntean, Rebecca
Hill, Sarah J.
Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title_full Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title_fullStr Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title_full_unstemmed Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title_short Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title_sort acute pr3-anca vasculitis in an asymptomatic covid-19 teenager
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554009/
https://www.ncbi.nlm.nih.gov/pubmed/34729348
http://dx.doi.org/10.1016/j.epsc.2021.102103
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