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Case Report: Identification of a Novel GNAS Mutation and 1p/22q Co-Deletion in a Patient With Multiple Recurrent Meningiomas Sensitive to Sunitinib

BACKGROUND: Although surgical resection can cure the majority of meningiomas, there are still approximately 20% of patients suffering from an aggressive course with recurrence or progression. In this study, we reported a novel GNAS mutation and 1p/22q co-deletion responding to sunitinib in a patient...

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Detalles Bibliográficos
Autores principales: Hong, Weiping, Shan, Changguo, Ye, Minting, Yang, Yanying, Wang, Hui, Du, Furong, Zhang, Xing, Song, Chao, Cai, Linbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554081/
https://www.ncbi.nlm.nih.gov/pubmed/34722286
http://dx.doi.org/10.3389/fonc.2021.737523