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RNA-Containing Immune Complexes Formed by Anti-Melanoma Differentiation Associated Gene 5 Autoantibody Are Potent Inducers of IFN-α

OBJECTIVE: Anti-melanoma differentiation-associated gene 5 (MDA5) autoantibody is a distinctive serology hallmark of dermatomyositis (DM). As an autoantigen, MDA5 is a cytoplasmic RNA recognition receptor. The aim of this study was to address the question of whether the RNA-containing immune complex...

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Detalles Bibliográficos
Autores principales:	Wang, Kaiwen, Zhao, Jiangfeng, Wu, Wanlong, Xu, Wenwen, Sun, Shuhui, Chen, Zhiwei, Fu, Yakai, Guo, Li, Du, Hui, Ye, Shuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554111/ https://www.ncbi.nlm.nih.gov/pubmed/34721411 http://dx.doi.org/10.3389/fimmu.2021.743704

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