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Effects of Tumor-Derived Exosome Programmed Death Ligand 1 on Tumor Immunity and Clinical Applications

Programmed death ligand 1 (PD-L1) is a typical immune surface protein that binds to programmed cell death 1 (PD-1) on T cells through its extracellular domain. Subsequently, T cell activity is inhibited, and tumor immune tolerance is enhanced. Anti-PD-1/PD-L1 immune checkpoint therapy blocks the com...

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Detalles Bibliográficos
Autores principales: Shao, Bo, Dang, Qin, Chen, Zhuang, Chen, Chen, Zhou, Quanbo, Qiao, Bingbing, Liu, Jinbo, Hu, Shengyun, Wang, Guixian, Yuan, Weitang, Sun, Zhenqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554115/
https://www.ncbi.nlm.nih.gov/pubmed/34722545
http://dx.doi.org/10.3389/fcell.2021.760211