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Local Ancestry Adjusted Allelic Association Analysis Robustly Captures Tuberculosis Susceptibility Loci

Pulmonary tuberculosis (TB), caused by Mycobacterium tuberculosis, is a complex disease. The risk of developing active TB is in part determined by host genetic factors. Most genetic studies investigating TB susceptibility fail to replicate association signals particularly across diverse populations....

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Detalles Bibliográficos
Autores principales: Swart, Yolandi, Uren, Caitlin, van Helden, Paul D., Hoal, Eileen G., Möller, Marlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554120/
https://www.ncbi.nlm.nih.gov/pubmed/34721521
http://dx.doi.org/10.3389/fgene.2021.716558