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A Systematic Review of Transcriptional Dysregulation in Huntington’s Disease Studied by RNA Sequencing

Huntington’s disease (HD) is a chronic neurodegenerative disorder caused by an expansion of polyglutamine repeats in exon 1 of the Huntingtin gene. Transcriptional dysregulation accompanied by epigenetic alterations is an early and central disease mechanism in HD yet, the exact mechanisms and regula...

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Detalles Bibliográficos
Autores principales:	Malla, Bimala, Guo, Xuanzong, Senger, Gökçe, Chasapopoulou, Zoi, Yildirim, Ferah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554124/ https://www.ncbi.nlm.nih.gov/pubmed/34721539 http://dx.doi.org/10.3389/fgene.2021.751033

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