Dexamethasone-Induced FKBP51 Expression in CD4(+) T-Lymphocytes Is Uniquely Associated With Worse Asthma Control in Obese Children With Asthma

INTRODUCTION: There is evidence that obesity, a risk factor for asthma severity and morbidity, has a unique asthma phenotype which is less atopic and less responsive to inhaled corticosteroids (ICS). Peripheral blood mononuclear cells (PBMC) are important to the immunologic pathways of obese asthma...

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Detalles Bibliográficos
Autores principales: Tejwani, Vickram, McCormack, Amanda, Suresh, Karthik, Woo, Han, Xu, Ningchun, Davis, Meghan F., Brigham, Emily, Hansel, Nadia N., McCormack, Meredith C., D’Alessio, Franco R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554235/
https://www.ncbi.nlm.nih.gov/pubmed/34721414
http://dx.doi.org/10.3389/fimmu.2021.744782

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