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Small conductance calcium activated K(+) channel inhibitor decreases stretch induced vulnerability to atrial fibrillation

BACKGROUND: Atrial dilation is an important risk factor for atrial fibrillation (AF) and animal studies have found that acute atrial dilation shortens the atrial effective refractory period (AERP) and increases the risk of AF. Stretch activated ion channels (SACs) and calcium channels play a role in...

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Detalles Bibliográficos
Autores principales: Yan, Yannan, Skarsfeldt, Mark Alexander, Diness, Jonas Goldin, Bentzen, Bo Hjorth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554272/
https://www.ncbi.nlm.nih.gov/pubmed/34746364
http://dx.doi.org/10.1016/j.ijcha.2021.100898