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Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women
Granulomatous mastitis (GM) is an underdiagnosed and understudied benign inflammatory disease of the breast whose accurate diagnosis is confounded by mimicry of other breast pathologies (infectious mastitis and abscess, malignancy) and limited clinician knowledge of the disease. GM disproportionatel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554342/ https://www.ncbi.nlm.nih.gov/pubmed/34745405 http://dx.doi.org/10.1016/j.radcr.2021.09.044 |
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author | Bacon, Daniel R. Ngeve, Smith M. Jordan, Sheryl G. |
author_facet | Bacon, Daniel R. Ngeve, Smith M. Jordan, Sheryl G. |
author_sort | Bacon, Daniel R. |
collection | PubMed |
description | Granulomatous mastitis (GM) is an underdiagnosed and understudied benign inflammatory disease of the breast whose accurate diagnosis is confounded by mimicry of other breast pathologies (infectious mastitis and abscess, malignancy) and limited clinician knowledge of the disease. GM disproportionately affects minority women, furthering health disparities for a demographic already disadvantaged in the care of breast diseases. The first step in diagnosis is ultrasound followed by core needle biopsy yielding granulomatous inflammation. To far lesser degree, mammography, and MRI may play a role in narrowing the differential. A high index of clinical suspicion and multidisciplinary approach is required. The presence of Corynebacterium kroppensteddti may indicate one subtype of granulomatous mastitis called cystic neutrophilic granulomatous mastitis; disease stratification, and individualized therapy are on the horizon. |
format | Online Article Text |
id | pubmed-8554342 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-85543422021-11-05 Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women Bacon, Daniel R. Ngeve, Smith M. Jordan, Sheryl G. Radiol Case Rep Case Report Granulomatous mastitis (GM) is an underdiagnosed and understudied benign inflammatory disease of the breast whose accurate diagnosis is confounded by mimicry of other breast pathologies (infectious mastitis and abscess, malignancy) and limited clinician knowledge of the disease. GM disproportionately affects minority women, furthering health disparities for a demographic already disadvantaged in the care of breast diseases. The first step in diagnosis is ultrasound followed by core needle biopsy yielding granulomatous inflammation. To far lesser degree, mammography, and MRI may play a role in narrowing the differential. A high index of clinical suspicion and multidisciplinary approach is required. The presence of Corynebacterium kroppensteddti may indicate one subtype of granulomatous mastitis called cystic neutrophilic granulomatous mastitis; disease stratification, and individualized therapy are on the horizon. Elsevier 2021-10-22 /pmc/articles/PMC8554342/ /pubmed/34745405 http://dx.doi.org/10.1016/j.radcr.2021.09.044 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Bacon, Daniel R. Ngeve, Smith M. Jordan, Sheryl G. Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women |
title | Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women |
title_full | Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women |
title_fullStr | Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women |
title_full_unstemmed | Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women |
title_short | Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women |
title_sort | granulomatous mastitis: an underdiagnosed inflammatory disease afflicting minority women |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554342/ https://www.ncbi.nlm.nih.gov/pubmed/34745405 http://dx.doi.org/10.1016/j.radcr.2021.09.044 |
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