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Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women

Granulomatous mastitis (GM) is an underdiagnosed and understudied benign inflammatory disease of the breast whose accurate diagnosis is confounded by mimicry of other breast pathologies (infectious mastitis and abscess, malignancy) and limited clinician knowledge of the disease. GM disproportionatel...

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Autores principales: Bacon, Daniel R., Ngeve, Smith M., Jordan, Sheryl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554342/
https://www.ncbi.nlm.nih.gov/pubmed/34745405
http://dx.doi.org/10.1016/j.radcr.2021.09.044
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author Bacon, Daniel R.
Ngeve, Smith M.
Jordan, Sheryl G.
author_facet Bacon, Daniel R.
Ngeve, Smith M.
Jordan, Sheryl G.
author_sort Bacon, Daniel R.
collection PubMed
description Granulomatous mastitis (GM) is an underdiagnosed and understudied benign inflammatory disease of the breast whose accurate diagnosis is confounded by mimicry of other breast pathologies (infectious mastitis and abscess, malignancy) and limited clinician knowledge of the disease. GM disproportionately affects minority women, furthering health disparities for a demographic already disadvantaged in the care of breast diseases. The first step in diagnosis is ultrasound followed by core needle biopsy yielding granulomatous inflammation. To far lesser degree, mammography, and MRI may play a role in narrowing the differential. A high index of clinical suspicion and multidisciplinary approach is required. The presence of Corynebacterium kroppensteddti may indicate one subtype of granulomatous mastitis called cystic neutrophilic granulomatous mastitis; disease stratification, and individualized therapy are on the horizon.
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spelling pubmed-85543422021-11-05 Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women Bacon, Daniel R. Ngeve, Smith M. Jordan, Sheryl G. Radiol Case Rep Case Report Granulomatous mastitis (GM) is an underdiagnosed and understudied benign inflammatory disease of the breast whose accurate diagnosis is confounded by mimicry of other breast pathologies (infectious mastitis and abscess, malignancy) and limited clinician knowledge of the disease. GM disproportionately affects minority women, furthering health disparities for a demographic already disadvantaged in the care of breast diseases. The first step in diagnosis is ultrasound followed by core needle biopsy yielding granulomatous inflammation. To far lesser degree, mammography, and MRI may play a role in narrowing the differential. A high index of clinical suspicion and multidisciplinary approach is required. The presence of Corynebacterium kroppensteddti may indicate one subtype of granulomatous mastitis called cystic neutrophilic granulomatous mastitis; disease stratification, and individualized therapy are on the horizon. Elsevier 2021-10-22 /pmc/articles/PMC8554342/ /pubmed/34745405 http://dx.doi.org/10.1016/j.radcr.2021.09.044 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Bacon, Daniel R.
Ngeve, Smith M.
Jordan, Sheryl G.
Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women
title Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women
title_full Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women
title_fullStr Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women
title_full_unstemmed Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women
title_short Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women
title_sort granulomatous mastitis: an underdiagnosed inflammatory disease afflicting minority women
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554342/
https://www.ncbi.nlm.nih.gov/pubmed/34745405
http://dx.doi.org/10.1016/j.radcr.2021.09.044
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