Food Protein-Induced Enterocolitis Syndrome Causing Hypovolemic Shock in Infants With Down Syndrome

This study aimed to investigate the clinical characteristics of severe food protein-induced enterocolitis syndrome (FPIES) in patients with Down syndrome. We report the cases of three infants with Down syndrome who were diagnosed with FPIES. All patients presented with hypovolemic shock, metabolic a...

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Detalles Bibliográficos
Autores principales: Iguchi, Akihiro, Aoki, Yoshihiro, Kitazawa, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554378/
https://www.ncbi.nlm.nih.gov/pubmed/34725615
http://dx.doi.org/10.7759/cureus.18366
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author Iguchi, Akihiro
Aoki, Yoshihiro
Kitazawa, Katsuhiko
author_facet Iguchi, Akihiro
Aoki, Yoshihiro
Kitazawa, Katsuhiko
author_sort Iguchi, Akihiro
collection PubMed
description This study aimed to investigate the clinical characteristics of severe food protein-induced enterocolitis syndrome (FPIES) in patients with Down syndrome. We report the cases of three infants with Down syndrome who were diagnosed with FPIES. All patients presented with hypovolemic shock, metabolic acidosis, and acute kidney injury after introducing a milk-based formula. They required aggressive fluid resuscitation and alternative nutrition. All three patients survived without any complications after the treatment. FPIES may cause hypovolemic shock in infants with Down syndrome and these patients need prompt fluid resuscitation.
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spelling pubmed-85543782021-10-31 Food Protein-Induced Enterocolitis Syndrome Causing Hypovolemic Shock in Infants With Down Syndrome Iguchi, Akihiro Aoki, Yoshihiro Kitazawa, Katsuhiko Cureus Pediatrics This study aimed to investigate the clinical characteristics of severe food protein-induced enterocolitis syndrome (FPIES) in patients with Down syndrome. We report the cases of three infants with Down syndrome who were diagnosed with FPIES. All patients presented with hypovolemic shock, metabolic acidosis, and acute kidney injury after introducing a milk-based formula. They required aggressive fluid resuscitation and alternative nutrition. All three patients survived without any complications after the treatment. FPIES may cause hypovolemic shock in infants with Down syndrome and these patients need prompt fluid resuscitation. Cureus 2021-09-28 /pmc/articles/PMC8554378/ /pubmed/34725615 http://dx.doi.org/10.7759/cureus.18366 Text en Copyright © 2021, Iguchi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Iguchi, Akihiro
Aoki, Yoshihiro
Kitazawa, Katsuhiko
Food Protein-Induced Enterocolitis Syndrome Causing Hypovolemic Shock in Infants With Down Syndrome
title Food Protein-Induced Enterocolitis Syndrome Causing Hypovolemic Shock in Infants With Down Syndrome
title_full Food Protein-Induced Enterocolitis Syndrome Causing Hypovolemic Shock in Infants With Down Syndrome
title_fullStr Food Protein-Induced Enterocolitis Syndrome Causing Hypovolemic Shock in Infants With Down Syndrome
title_full_unstemmed Food Protein-Induced Enterocolitis Syndrome Causing Hypovolemic Shock in Infants With Down Syndrome
title_short Food Protein-Induced Enterocolitis Syndrome Causing Hypovolemic Shock in Infants With Down Syndrome
title_sort food protein-induced enterocolitis syndrome causing hypovolemic shock in infants with down syndrome
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554378/
https://www.ncbi.nlm.nih.gov/pubmed/34725615
http://dx.doi.org/10.7759/cureus.18366
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AT kitazawakatsuhiko foodproteininducedenterocolitissyndromecausinghypovolemicshockininfantswithdownsyndrome

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