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Long‐term antagonism and allosteric regulation of mu opioid receptors by the novel ligand, methocinnamox

Opioid overdose is a leading cause of death in the United States. The only treatment available currently is the competitive antagonist, naloxone (Narcan(®)). Although naloxone is very effective and has saved many lives, as a competitive antagonist it has limitations. Due to the short half‐life of na...

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Detalles Bibliográficos
Autores principales: Zamora, Joshua C., Smith, Hudson R., Jennings, Elaine M., Chavera, Teresa S., Kotipalli, Varun, Jay, Aleasha, Husbands, Stephen M., Disney, Alex, Berg, Kelly A., Clarke, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554411/
https://www.ncbi.nlm.nih.gov/pubmed/34713624
http://dx.doi.org/10.1002/prp2.887