Assessing the necessity of a family of genes that encode small proteins in Dictyostelium discoideum development

Dictyostelium discoideum’s genome encodes for a large class of small proteins that are developmentally regulated. We deleted six of the genes that encode these proteins to determine if they play an essential role in Dictyostelium discoideum development. Deletion of these genes had no significant eff...

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Detalles Bibliográficos
Autores principales: Wu, Yumei, Williams, Felicia N, Scaglione, K Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
Negative Result
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554618/
https://www.ncbi.nlm.nih.gov/pubmed/34723153
http://dx.doi.org/10.17912/micropub.biology.000490
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author Wu, Yumei
Williams, Felicia N
Scaglione, K Matthew
author_facet Wu, Yumei
Williams, Felicia N
Scaglione, K Matthew
author_sort Wu, Yumei
collection PubMed
description Dictyostelium discoideum’s genome encodes for a large class of small proteins that are developmentally regulated. We deleted six of the genes that encode these proteins to determine if they play an essential role in Dictyostelium discoideum development. Deletion of these genes had no significant effect on Dictyostelium discoideum development. These results suggest that the selected genes do not play an essential role in Dictyostelium discoideum development.
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spelling pubmed-85546182021-10-29 Assessing the necessity of a family of genes that encode small proteins in Dictyostelium discoideum development Wu, Yumei Williams, Felicia N Scaglione, K Matthew MicroPubl Biol Negative Result Dictyostelium discoideum’s genome encodes for a large class of small proteins that are developmentally regulated. We deleted six of the genes that encode these proteins to determine if they play an essential role in Dictyostelium discoideum development. Deletion of these genes had no significant effect on Dictyostelium discoideum development. These results suggest that the selected genes do not play an essential role in Dictyostelium discoideum development. Caltech Library 2021-10-28 /pmc/articles/PMC8554618/ /pubmed/34723153 http://dx.doi.org/10.17912/micropub.biology.000490 Text en Copyright: © 2021 by the authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Negative Result
Wu, Yumei
Williams, Felicia N
Scaglione, K Matthew
Assessing the necessity of a family of genes that encode small proteins in Dictyostelium discoideum development
title Assessing the necessity of a family of genes that encode small proteins in Dictyostelium discoideum development
title_full Assessing the necessity of a family of genes that encode small proteins in Dictyostelium discoideum development
title_fullStr Assessing the necessity of a family of genes that encode small proteins in Dictyostelium discoideum development
title_full_unstemmed Assessing the necessity of a family of genes that encode small proteins in Dictyostelium discoideum development
title_short Assessing the necessity of a family of genes that encode small proteins in Dictyostelium discoideum development
title_sort assessing the necessity of a family of genes that encode small proteins in dictyostelium discoideum development
topic Negative Result
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554618/
https://www.ncbi.nlm.nih.gov/pubmed/34723153
http://dx.doi.org/10.17912/micropub.biology.000490
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AT scaglionekmatthew assessingthenecessityofafamilyofgenesthatencodesmallproteinsindictyosteliumdiscoideumdevelopment

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