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Direct conversion of adult fibroblasts into motor neurons

Generation of patient-derived neurons provides an unprecedented approach in modeling neurological diseases. Here, we describe the direct conversion of adult fibroblasts into motor neurons via lentiviral delivery of transcription factors. Compared with iPSC-based approach, directly converted neurons...

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Detalles Bibliográficos
Autores principales:	Sepehrimanesh, Masood, Akter, Masuma, Ding, Baojin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554625/ https://www.ncbi.nlm.nih.gov/pubmed/34746870 http://dx.doi.org/10.1016/j.xpro.2021.100917

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