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Lomerizine 2HCl inhibits cell proliferation and induces protective autophagy in colorectal cancer via the PI3K/Akt/mTOR signaling pathway

Colorectal cancer (CRC) is one of the most common malignancies currently. Despite advances in drug development, the survival and response rates in CRC patients are still poor. In our previous study, a library comprised of 1056 bioactive compounds was used for screening of drugs that could suppress C...

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Detalles Bibliográficos
Autores principales: Tan, Xiang‐Peng, He, Yan, Huang, Yun‐Na, Zheng, Can‐Can, Li, Jun‐Qi, Liu, Qin‐Wen, He, Ming‐Liang, Li, Bin, Xu, Wen‐Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554656/
https://www.ncbi.nlm.nih.gov/pubmed/34766155
http://dx.doi.org/10.1002/mco2.83