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Laboratory diagnosis and management of COVID-19 cases: creating a safe testing environment

BACKGROUND: COVID-19 disease has had a profound impact worldwide since it was discovered in Wuhan, China, in December 2019. Laboratory testing is crucial to prompt identification of positive cases, initiation of treatment and management strategies. However, medical scientists are vulnerable to infec...

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Autores principales: Lekan-Agunbiade, Titilayo Tosin, Agunbiade, Olalekan Isaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554734/
https://www.ncbi.nlm.nih.gov/pubmed/34715800
http://dx.doi.org/10.1186/s12879-021-06806-0
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author Lekan-Agunbiade, Titilayo Tosin
Agunbiade, Olalekan Isaiah
author_facet Lekan-Agunbiade, Titilayo Tosin
Agunbiade, Olalekan Isaiah
author_sort Lekan-Agunbiade, Titilayo Tosin
collection PubMed
description BACKGROUND: COVID-19 disease has had a profound impact worldwide since it was discovered in Wuhan, China, in December 2019. Laboratory testing is crucial to prompt identification of positive cases, initiation of treatment and management strategies. However, medical scientists are vulnerable to infection due to the risk of exposure in the laboratory and the community. This study sought to determine the awareness of laboratory safety measures, assess the personal efforts of medical scientists in creating a safe laboratory environment for testing and examine the laboratory safety enabling factors. METHODS: The data used for the study were generated among medical scientists in Nigeria through an internet-broadcasted questionnaire and were analyzed using IBM SPSS Statistics (version 25). RESULTS: The majority of the respondents had a high awareness of laboratory safety measures (60.3%) and demonstrated good personal efforts in creating a safe laboratory testing environment (63%). The level of awareness of laboratory safety measures was significantly associated with respondents’ level of education (χ(2) = 6.143; p = 0.046) and influences respondents’ efforts in creating a safe laboratory testing environment (p = 0.007). However, just a few respondents could convincingly attest to the availability of adequate and appropriate PPE with proper utilization training (45.1%), adequate rest and other welfare packages (45.8%) as well as access to appropriate Biological Safety Cabinets (BSCs) and other essential equipment in their laboratories (48.8%). Furthermore, a significant association existed between the availability of laboratory safety enabling factors and respondents’ efforts in creating a safe environment for testing with the p-value ranging between < 0.0001 and 0.003. CONCLUSION: This study revealed that despite the high awareness of safety measures and good personal efforts of the study participants in creating a safe laboratory-testing environment, there was poor availability of safety facilities, equipment, support and welfare packages required to enhance their safety. It is, therefore, crucial to provide necessary laboratory biosafety equipment and PPE in order not to compromise medical scientists’ safety as they perform their duties in COVID-19 pandemic response. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12879-021-06806-0.
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spelling pubmed-85547342021-10-29 Laboratory diagnosis and management of COVID-19 cases: creating a safe testing environment Lekan-Agunbiade, Titilayo Tosin Agunbiade, Olalekan Isaiah BMC Infect Dis Research Article BACKGROUND: COVID-19 disease has had a profound impact worldwide since it was discovered in Wuhan, China, in December 2019. Laboratory testing is crucial to prompt identification of positive cases, initiation of treatment and management strategies. However, medical scientists are vulnerable to infection due to the risk of exposure in the laboratory and the community. This study sought to determine the awareness of laboratory safety measures, assess the personal efforts of medical scientists in creating a safe laboratory environment for testing and examine the laboratory safety enabling factors. METHODS: The data used for the study were generated among medical scientists in Nigeria through an internet-broadcasted questionnaire and were analyzed using IBM SPSS Statistics (version 25). RESULTS: The majority of the respondents had a high awareness of laboratory safety measures (60.3%) and demonstrated good personal efforts in creating a safe laboratory testing environment (63%). The level of awareness of laboratory safety measures was significantly associated with respondents’ level of education (χ(2) = 6.143; p = 0.046) and influences respondents’ efforts in creating a safe laboratory testing environment (p = 0.007). However, just a few respondents could convincingly attest to the availability of adequate and appropriate PPE with proper utilization training (45.1%), adequate rest and other welfare packages (45.8%) as well as access to appropriate Biological Safety Cabinets (BSCs) and other essential equipment in their laboratories (48.8%). Furthermore, a significant association existed between the availability of laboratory safety enabling factors and respondents’ efforts in creating a safe environment for testing with the p-value ranging between < 0.0001 and 0.003. CONCLUSION: This study revealed that despite the high awareness of safety measures and good personal efforts of the study participants in creating a safe laboratory-testing environment, there was poor availability of safety facilities, equipment, support and welfare packages required to enhance their safety. It is, therefore, crucial to provide necessary laboratory biosafety equipment and PPE in order not to compromise medical scientists’ safety as they perform their duties in COVID-19 pandemic response. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12879-021-06806-0. BioMed Central 2021-10-29 /pmc/articles/PMC8554734/ /pubmed/34715800 http://dx.doi.org/10.1186/s12879-021-06806-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Lekan-Agunbiade, Titilayo Tosin
Agunbiade, Olalekan Isaiah
Laboratory diagnosis and management of COVID-19 cases: creating a safe testing environment
title Laboratory diagnosis and management of COVID-19 cases: creating a safe testing environment
title_full Laboratory diagnosis and management of COVID-19 cases: creating a safe testing environment
title_fullStr Laboratory diagnosis and management of COVID-19 cases: creating a safe testing environment
title_full_unstemmed Laboratory diagnosis and management of COVID-19 cases: creating a safe testing environment
title_short Laboratory diagnosis and management of COVID-19 cases: creating a safe testing environment
title_sort laboratory diagnosis and management of covid-19 cases: creating a safe testing environment
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554734/
https://www.ncbi.nlm.nih.gov/pubmed/34715800
http://dx.doi.org/10.1186/s12879-021-06806-0
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