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Myelomonocytic skewing in chronic myelomonocytic leukemia: phenotypic, molecular and biologic features and impact on survival

BACKGROUND: Myelomonocytic skewing is considered as a key pathophysiologic phenomenon in chronic myelomonocytic leukemia (CMML), but its prevalence and potential correlation with phenotypic, genotypic, and clinical features are poorly defined. METHODS: Skewed differentiation toward the myelomonocyti...

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Detalles Bibliográficos
Autores principales: Geissler, Klaus, Jäger, Eva, Barna, Agnes, Graf, Temeida, Graf, Elmir, Öhler, Leopold, Hoermann, Gregor, Valent, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554855/
https://www.ncbi.nlm.nih.gov/pubmed/33432601
http://dx.doi.org/10.1111/ejh.13577

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