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The role of MORC3 in silencing transposable elements in mouse embryonic stem cells

BACKGROUND: Microrchidia proteins (MORCs) are involved in epigenetic gene silencing in a variety of eukaryotic organisms. Deletion of MORCs result in several developmental abnormalities and their dysregulation has been implicated in developmental disease and multiple cancers. Specifically, mammalian...

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Detalles Bibliográficos
Autores principales:	Desai, Varsha P., Chouaref, Jihed, Wu, Haoyu, Pastor, William A., Kan, Ryan L., Oey, Harald M., Li, Zheng, Ho, Jamie, Vonk, Kelly K. D., San Leon Granado, David, Christopher, Michael A., Clark, Amander T., Jacobsen, Steven E., Daxinger, Lucia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555065/ https://www.ncbi.nlm.nih.gov/pubmed/34706774 http://dx.doi.org/10.1186/s13072-021-00420-9

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