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Technical challenges regarding the use of formalin-fixed paraffin embedded (FFPE) tissue specimens for the detection of bacterial alterations in colorectal cancer

BACKGROUND: Formalin-fixed paraffin embedded (FFPE) tissues may provide an exciting resource to study microbial associations in human disease, but the use of these low biomass specimens remains challenging. We aimed to reduce unintentional bacterial interference in molecular analysis of FFPE tissues...

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Detalles Bibliográficos
Autores principales: Lam, Suk Yee, Ioannou, Athanasia, Konstanti, Prokopis, Visseren, Thijmen, Doukas, Michail, Peppelenbosch, Maikel Petrus, Belzer, Clara, Fuhler, Gwenny Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555202/
https://www.ncbi.nlm.nih.gov/pubmed/34715774
http://dx.doi.org/10.1186/s12866-021-02359-z