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Technical challenges regarding the use of formalin-fixed paraffin embedded (FFPE) tissue specimens for the detection of bacterial alterations in colorectal cancer
BACKGROUND: Formalin-fixed paraffin embedded (FFPE) tissues may provide an exciting resource to study microbial associations in human disease, but the use of these low biomass specimens remains challenging. We aimed to reduce unintentional bacterial interference in molecular analysis of FFPE tissues...
Autores principales: | Lam, Suk Yee, Ioannou, Athanasia, Konstanti, Prokopis, Visseren, Thijmen, Doukas, Michail, Peppelenbosch, Maikel Petrus, Belzer, Clara, Fuhler, Gwenny Manel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555202/ https://www.ncbi.nlm.nih.gov/pubmed/34715774 http://dx.doi.org/10.1186/s12866-021-02359-z |
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