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IκB kinase promotes Nrf2 ubiquitination and degradation by phosphorylating cylindromatosis, aggravating oxidative stress injury in obesity-related nephropathy

BACKGROUND: Obesity-related nephropathy (ORN) has become one of the leading causes of end-stage renal disease and has tripled over the past decade. Previous studies have demonstrated that decreased reactive oxygen species production may contribute to improving ORN by ameliorating oxidative stress in...

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Detalles Bibliográficos
Autores principales:	Chen, Yin-Yin, Hong, Han, Lei, Yu-Ting, Zou, Jia, Yang, Yi-Ya, He, Li-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555227/ https://www.ncbi.nlm.nih.gov/pubmed/34711178 http://dx.doi.org/10.1186/s10020-021-00398-w

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