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Anemia among children living with HIV/AIDS on HAART in Mekelle Hospital, Tigray regional state of northern ethiopia – a cross-sectional study

BACKGROUND: Anemia is a common complication of HIV/AIDS in children. There is lack of evidence on anemia prevalence among children living with HIV/AIDS on highly active antiretroviral therapy (HAART) in Tigray regional state, which the current study aimed to generate. METHODS: An institution-based c...

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Autores principales: Tesfay, Feven, Gebregerges, Abrha, Gebrehiwot, Haftay, Hailekiros, Haftu, Girmay, Letegebriel, Bekuretsion, Hadush, Gebrezigher, Gebrekidan, Gebremariam, Gebreslassie, Teklehaimanot, Gebreyohannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555256/
https://www.ncbi.nlm.nih.gov/pubmed/34715844
http://dx.doi.org/10.1186/s12887-021-02960-1
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author Tesfay, Feven
Gebregerges, Abrha
Gebrehiwot, Haftay
Hailekiros, Haftu
Girmay, Letegebriel
Bekuretsion, Hadush
Gebrezigher, Gebrekidan
Gebremariam, Gebreslassie
Teklehaimanot, Gebreyohannes
author_facet Tesfay, Feven
Gebregerges, Abrha
Gebrehiwot, Haftay
Hailekiros, Haftu
Girmay, Letegebriel
Bekuretsion, Hadush
Gebrezigher, Gebrekidan
Gebremariam, Gebreslassie
Teklehaimanot, Gebreyohannes
author_sort Tesfay, Feven
collection PubMed
description BACKGROUND: Anemia is a common complication of HIV/AIDS in children. There is lack of evidence on anemia prevalence among children living with HIV/AIDS on highly active antiretroviral therapy (HAART) in Tigray regional state, which the current study aimed to generate. METHODS: An institution-based cross-sectional study was conducted on 241 children living with HIV/AIDS on HAART attending the antiretroviral therapy (ART) clinic of Mekelle hospital from November 2018-January 2019. Socio-demographic data were collected using a structured pretested questionnaire. Participants’ hemoglobin level was utilized to determine the prevalence of anemia. WHO cut-off values for Hgb were used to categorise the severity of anemia. Microscopic examination was performed for morphological classification of anemia. RESULTS: Among the participants, 7 % (n = 16) were anemic in this study. Of these, 56 %, 19 %, and 25 % had mild, moderate, and severe anemia, respectively. Morphologically, normocytic-normochromic anemia was found the most common type of anemia in this study. CONCLUSIONS: The prevalence of anemia among participants was low in this study. However, a considerable proportion of participants had severe anemia, requiring regular monitoring of anemia status in these patients for better clinical outcomes and quality of life improvements.
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spelling pubmed-85552562021-10-29 Anemia among children living with HIV/AIDS on HAART in Mekelle Hospital, Tigray regional state of northern ethiopia – a cross-sectional study Tesfay, Feven Gebregerges, Abrha Gebrehiwot, Haftay Hailekiros, Haftu Girmay, Letegebriel Bekuretsion, Hadush Gebrezigher, Gebrekidan Gebremariam, Gebreslassie Teklehaimanot, Gebreyohannes BMC Pediatr Research BACKGROUND: Anemia is a common complication of HIV/AIDS in children. There is lack of evidence on anemia prevalence among children living with HIV/AIDS on highly active antiretroviral therapy (HAART) in Tigray regional state, which the current study aimed to generate. METHODS: An institution-based cross-sectional study was conducted on 241 children living with HIV/AIDS on HAART attending the antiretroviral therapy (ART) clinic of Mekelle hospital from November 2018-January 2019. Socio-demographic data were collected using a structured pretested questionnaire. Participants’ hemoglobin level was utilized to determine the prevalence of anemia. WHO cut-off values for Hgb were used to categorise the severity of anemia. Microscopic examination was performed for morphological classification of anemia. RESULTS: Among the participants, 7 % (n = 16) were anemic in this study. Of these, 56 %, 19 %, and 25 % had mild, moderate, and severe anemia, respectively. Morphologically, normocytic-normochromic anemia was found the most common type of anemia in this study. CONCLUSIONS: The prevalence of anemia among participants was low in this study. However, a considerable proportion of participants had severe anemia, requiring regular monitoring of anemia status in these patients for better clinical outcomes and quality of life improvements. BioMed Central 2021-10-29 /pmc/articles/PMC8555256/ /pubmed/34715844 http://dx.doi.org/10.1186/s12887-021-02960-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Tesfay, Feven
Gebregerges, Abrha
Gebrehiwot, Haftay
Hailekiros, Haftu
Girmay, Letegebriel
Bekuretsion, Hadush
Gebrezigher, Gebrekidan
Gebremariam, Gebreslassie
Teklehaimanot, Gebreyohannes
Anemia among children living with HIV/AIDS on HAART in Mekelle Hospital, Tigray regional state of northern ethiopia – a cross-sectional study
title Anemia among children living with HIV/AIDS on HAART in Mekelle Hospital, Tigray regional state of northern ethiopia – a cross-sectional study
title_full Anemia among children living with HIV/AIDS on HAART in Mekelle Hospital, Tigray regional state of northern ethiopia – a cross-sectional study
title_fullStr Anemia among children living with HIV/AIDS on HAART in Mekelle Hospital, Tigray regional state of northern ethiopia – a cross-sectional study
title_full_unstemmed Anemia among children living with HIV/AIDS on HAART in Mekelle Hospital, Tigray regional state of northern ethiopia – a cross-sectional study
title_short Anemia among children living with HIV/AIDS on HAART in Mekelle Hospital, Tigray regional state of northern ethiopia – a cross-sectional study
title_sort anemia among children living with hiv/aids on haart in mekelle hospital, tigray regional state of northern ethiopia – a cross-sectional study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555256/
https://www.ncbi.nlm.nih.gov/pubmed/34715844
http://dx.doi.org/10.1186/s12887-021-02960-1
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