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Xanthogranulomatous pyelonephritis infected with the Providencia stuartii: a case report and literature review

BACKGROUND: Xanthogranulomatous pyelonephritis (XGP) is a rare and severe chronic inflammatory disease of the renal parenchyma, which is most commonly associated with super-infections by bacteria such as E. coli, Proteus mirabilis, and occasionally Pseudomonas species. CASE PRESENTATION: Herein, we...

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Autores principales: Xu, Zhunan, Cai, Tong, Zhang, Xuebao, Wu, Jitao, Liu, Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555333/
https://www.ncbi.nlm.nih.gov/pubmed/34715795
http://dx.doi.org/10.1186/s12882-021-02565-x
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author Xu, Zhunan
Cai, Tong
Zhang, Xuebao
Wu, Jitao
Liu, Chu
author_facet Xu, Zhunan
Cai, Tong
Zhang, Xuebao
Wu, Jitao
Liu, Chu
author_sort Xu, Zhunan
collection PubMed
description BACKGROUND: Xanthogranulomatous pyelonephritis (XGP) is a rare and severe chronic inflammatory disease of the renal parenchyma, which is most commonly associated with super-infections by bacteria such as E. coli, Proteus mirabilis, and occasionally Pseudomonas species. CASE PRESENTATION: Herein, we present a rare case of a patient with XGP infected with Providencia stuartii. Initially, the patient refused nephrectomy and underwent holmium laser lithotripsy and right ureteral stenting, followed by meropenem treatment of 7 days. Relapse occurred in the third month after discharge from the hospital, due to which she underwent a radical nephrectomy. DISCUSSION: The diagnosis of XGP is confirmed by histopathology. The standard treatment for XGP is antibiotic therapy and radical nephrectomy, but partial nephrectomy may be appropriate in select cases.
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spelling pubmed-85553332021-10-29 Xanthogranulomatous pyelonephritis infected with the Providencia stuartii: a case report and literature review Xu, Zhunan Cai, Tong Zhang, Xuebao Wu, Jitao Liu, Chu BMC Nephrol Case Report BACKGROUND: Xanthogranulomatous pyelonephritis (XGP) is a rare and severe chronic inflammatory disease of the renal parenchyma, which is most commonly associated with super-infections by bacteria such as E. coli, Proteus mirabilis, and occasionally Pseudomonas species. CASE PRESENTATION: Herein, we present a rare case of a patient with XGP infected with Providencia stuartii. Initially, the patient refused nephrectomy and underwent holmium laser lithotripsy and right ureteral stenting, followed by meropenem treatment of 7 days. Relapse occurred in the third month after discharge from the hospital, due to which she underwent a radical nephrectomy. DISCUSSION: The diagnosis of XGP is confirmed by histopathology. The standard treatment for XGP is antibiotic therapy and radical nephrectomy, but partial nephrectomy may be appropriate in select cases. BioMed Central 2021-10-29 /pmc/articles/PMC8555333/ /pubmed/34715795 http://dx.doi.org/10.1186/s12882-021-02565-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Xu, Zhunan
Cai, Tong
Zhang, Xuebao
Wu, Jitao
Liu, Chu
Xanthogranulomatous pyelonephritis infected with the Providencia stuartii: a case report and literature review
title Xanthogranulomatous pyelonephritis infected with the Providencia stuartii: a case report and literature review
title_full Xanthogranulomatous pyelonephritis infected with the Providencia stuartii: a case report and literature review
title_fullStr Xanthogranulomatous pyelonephritis infected with the Providencia stuartii: a case report and literature review
title_full_unstemmed Xanthogranulomatous pyelonephritis infected with the Providencia stuartii: a case report and literature review
title_short Xanthogranulomatous pyelonephritis infected with the Providencia stuartii: a case report and literature review
title_sort xanthogranulomatous pyelonephritis infected with the providencia stuartii: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555333/
https://www.ncbi.nlm.nih.gov/pubmed/34715795
http://dx.doi.org/10.1186/s12882-021-02565-x
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