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Proteo-transcriptomics meta-analysis identifies SUMO2 as a promising target in glioblastoma multiforme therapeutics

BACKGROUND: Glioblastoma multiforme (GBM) is a deadly brain tumour with minimal survival rates due to the ever-expanding heterogeneity, chemo and radioresistance. Kinases are known to crucially drive GBM pathology; however, a rationale therapeutic combination that can simultaneously inhibit multiple...

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Detalles Bibliográficos
Autores principales: Krishna, Aswani P., John, Sebastian, Shinde, Puja Laxmanrao, Mishra, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555349/
https://www.ncbi.nlm.nih.gov/pubmed/34715855
http://dx.doi.org/10.1186/s12935-021-02279-y

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